Department of Chemical &amp; Physical Sciences / en 12 老司机直播 researchers recognized with Connaught Innovation Awards /celebrates/12-u-t-researchers-recognized-connaught-innovation-awards <span class="field field--name-title field--type-string field--label-hidden">12 老司机直播 researchers recognized with Connaught Innovation Awards</span> <div class="field field--name-field-awards-type field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/celebrates/awards-type/research-innovation" hreflang="en">Research &amp; Innovation</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>lanthierj</span></span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2023-06-01T14:09:19-04:00" title="Thursday, June 1, 2023 - 14:09" class="datetime">Thu, 06/01/2023 - 14:09</time> </span> <div class="field field--name-field-awards-people field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/celebrates/awards-people/faculty" hreflang="en">Faculty</a></div> </div> <div class="field field--name-field-awards-campus field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/celebrates/awards-campus/mississauga" hreflang="en">Mississauga</a></div> <div class="field__item"><a href="/celebrates/awards-campus/st-george" hreflang="en">St. George</a></div> </div> <div class="field field--name-field-awards-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/celebrates/awards-tags/connaught-innovation-award" hreflang="en">Connaught Innovation Award</a></div> <div class="field__item"><a href="/celebrates/awards-tags/department-chemical-physical-sciences" hreflang="en">Department of Chemical &amp; Physical Sciences</a></div> <div class="field__item"><a href="/celebrates/awards-tags/department-chemistry" hreflang="en">Department of Chemistry</a></div> <div class="field__item"><a href="/celebrates/awards-tags/department-electrical-computer-engineering" hreflang="en">Department of Electrical &amp; Computer Engineering</a></div> <div class="field__item"><a href="/celebrates/awards-tags/department-materials-science-engineering" hreflang="en">Department of Materials Science &amp; Engineering</a></div> <div class="field__item"><a href="/celebrates/awards-tags/department-molecular-genetics" hreflang="en">Department of Molecular Genetics</a></div> <div class="field__item"><a href="/celebrates/awards-tags/faculty-applied-science-engineering" hreflang="en">Faculty of Applied Science &amp; Engineering</a></div> <div class="field__item"><a href="/celebrates/awards-tags/faculty-arts-science" hreflang="en">Faculty of Arts &amp; Science</a></div> <div class="field__item"><a href="/celebrates/awards-tags/ibme" hreflang="en">IBME</a></div> <div class="field__item"><a href="/celebrates/awards-tags/temerty-faculty-medicine" hreflang="en">Temerty Faculty of Medicine</a></div> <div class="field__item"><a href="/celebrates/awards-tags/university-toronto-mississauga" hreflang="en">University of Toronto Mississauga</a></div> </div> <div class="field field--name-field-image-orientation field--type-list-string field--label-hidden field__item">landscape</div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p class="MsoNoSpacing">Twelve researchers at the University of Toronto are receiving Connaught Innovation Awards to help accelerate the development and commercialization of promising technologies with strong socio-economic potential that will have a positive impact on society.</p> <p class="MsoNoSpacing">鈥淭he University of Toronto congratulates this year鈥檚 recipients, whose work is addressing some of society鈥檚 most important challenges,鈥 said <b>Leah Cowen</b>, 老司机直播鈥檚 vice-president, research and innovation, and strategic initiatives. 鈥淔rom energy-saving windows to the use of plant hormones as appetite suppressants or the development of therapeutic targets that hold promise for a broad range of neurodegenerative diseases, these researchers鈥 inventions have the potential to make life-changing impacts here in Canada and around the world.鈥</p> <p class="MsoNoSpacing">This year's recipients are:</p> <ul> <li class="MsoNoSpacing"><a href="https://bme.utoronto.ca/faculty-research/core-faculty/julie-audet/"><strong>Julie Audet</strong>, Institute of&nbsp;Biomedical Engineering</a>: &nbsp;A tool to optimize complex formulations based on evolutionary computation accelerated by artificial neural networks</li> <li class="MsoNoSpacing"><a href="https://physiology.utoronto.ca/faculty/denise-belsham"><strong>Denise Belsham</strong>, department of physiology</a>: The use of a plant hormone CX as an appetite suppressant</li> <li class="MsoNoSpacing"><a href="https://moleculargenetics.utoronto.ca/faculty/alan-cochrane"><strong>Alan Cochrane</strong>, department of molecular genetics</a>: Development of broad-spectrum, host-directed antivirals</li> <li class="MsoNoSpacing"><a href="https://golovin.mie.utoronto.ca/"><strong>Kevin Golovin</strong>, department of mechanical and industrial engineering</a>: Reducing microplastic fibre pollution using low friction polymer brush as textile coatings</li> <li class="MsoNoSpacing"><a href="https://www.eecg.utoronto.ca/~gulak/home.php"><strong>Glenn Gulak</strong>, department of electrical and computer engineering</a>: A hardware accelerator for fully homomorphic encryption-based machine learning applications</li> <li class="MsoNoSpacing"><a href="https://www.utm.utoronto.ca/cps/people/patrick-gunning"><strong>Patrick Gunning</strong>, department of chemical and physical sciences</a>, University of Toronto Mississauga: Development of an artificial intelligence-driven platform to explore the undruggable genome</li> <li class="MsoNoSpacing"><a href="https://mse.utoronto.ca/faculty-staff/professors/hatton/"><strong>Benjamin Hatton</strong>, department of materials science and engineering</a>: Smart building facades for scalable operational energy management</li> <li class="MsoNoSpacing"><a href="https://www.chemistry.utoronto.ca/people/directories/all-faculty/ronald-kluger"><strong>Ronald Kluger</strong>, department of chemistry</a>: Production and evaluation of hemoglobin-bis-tetramers for oxygen transport to increase supply of lungs for transplant by enhancing ex vivo perfusion of donor lungs</li> <li class="MsoNoSpacing"><a href="https://www.chemistry.utoronto.ca/people/directories/all-faculty/eugenia-kumacheva"><strong>Eugenia Kumacheva</strong>, department of chemistry</a>: A platform for safety evaluation of chemical agents</li> <li class="MsoNoSpacing"><a href="https://lmp.utoronto.ca/faculty/janice-robertson"><strong>Janice Robertson</strong>, department of laboratory medicine and pathobiology</a>: Targeting TDP-43 aggregation as therapeutics for TDP-43 proteinopathies</li> <li class="MsoNoSpacing"><a href="https://news.engineering.utoronto.ca/non-invasive-approach-for-electrical-nerve-stimulation-among-five-projects-supported-by-2023-connaught-innovation-awards/"><strong>Paul Yoo</strong>, Institute of Biomedical Engineering</a>: Novel electrodes for non-invasive electrical nerve stimulation</li> <li class="MsoNoSpacing"><a href="https://mse.utoronto.ca/faculty-staff/professors/zou-yu/"><strong>Yu Zou</strong>, department of materials science and engineering</a>: Autonomous additive manufacturing system&nbsp;</li> </ul> <p class="MsoNoSpacing">The Connaught Innovation Award, which provides one-time seed funding to support the development and commercialization of the researchers鈥 innovative technologies, is backed by <a href="https://connaught.research.utoronto.ca/">the Connaught Fund</a> 鈥 the <a href="https://connaught.research.utoronto.ca/opportunities">largest internal university research funding program in Canada</a>. Established 50 years ago through the sale of Connaught Medical Research Laboratories, which is known for the discovery and production of insulin, the fund supports 老司机直播 scholars through programs such as&nbsp;the <a href="https://research.utoronto.ca/funding-opportunities/db/connaught-new-researcher-award">Connaught New Researcher Award</a>, the <a href="https://research.utoronto.ca/funding-opportunities/community-partnership-research-program-0">Connaught Community Partnership Research Program</a>,&nbsp;the <a href="https://brn.utoronto.ca/opportunity/connaught-challenge/">Connaught Major Research Challenge for Black Researchers</a><b>,</b>&nbsp;<a href="https://research.utoronto.ca/funding-opportunities/db/mclean-award">the McLean Award</a>&nbsp;and international doctoral scholarships.</p> <p class="MsoNoSpacing">&nbsp;</p> </div> <div class="field field--name-field-source field--type-string field--label-hidden field__item">UTC</div> <div class="field field--name-field-top-story-hub-page- field--type-boolean field--label-above"> <div class="field__label">Top Story (Hub page)</div> <div class="field__item">Off</div> </div> Thu, 01 Jun 2023 18:09:19 +0000 lanthierj 301839 at Patrick Gunning recognized with Connaught Innovation Award /celebrates/patrick-gunning-recognized-connaught-innovation-award <span class="field field--name-title field--type-string field--label-hidden">Patrick Gunning recognized with Connaught Innovation Award</span> <div class="field field--name-field-awards-type field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/celebrates/awards-type/research-innovation" hreflang="en">Research &amp; Innovation</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>lanthierj</span></span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2021-03-29T06:56:42-04:00" title="Monday, March 29, 2021 - 06:56" class="datetime">Mon, 03/29/2021 - 06:56</time> </span> <div class="field field--name-field-awards-people field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/celebrates/awards-people/faculty" hreflang="en">Faculty</a></div> </div> <div class="field field--name-field-awards-campus field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/celebrates/awards-campus/st-george" hreflang="en">St. George</a></div> </div> <div class="field field--name-field-awards-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/celebrates/awards-tags/connaught-innovation-award" hreflang="en">Connaught Innovation Award</a></div> <div class="field__item"><a href="/celebrates/awards-tags/u-t-mississauga" hreflang="en">老司机直播 Mississauga</a></div> <div class="field__item"><a href="/celebrates/awards-tags/department-chemical-physical-sciences" hreflang="en">Department of Chemical &amp; Physical Sciences</a></div> </div> <div class="field field--name-field-image-orientation field--type-list-string field--label-hidden field__item">landscape</div> <div class="field field--name-field-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/media/DSC_3314-Edit-2-crop.jpg" width="750" height="500" alt="&quot;&quot;"> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Professor <strong>Patrick Gunning</strong> of the department of chemical and physical sciences at the University of Toronto Mississauga has received a Connaught Innovation Award for his team's work on HDAC6 inhibitors to treat&nbsp;hematological malignancies 鈥 cancers that affect the blood, bone marrow, and lymph nodes.</p> <p>A Canada Research Chair in Medicinal Chemistry and the director of the Centre for Medicinal Chemistry, Gunning has founded three pharmaceutical companies with more than&nbsp;$22 million&nbsp;in funding&nbsp;and has developed a dynamic and diverse medicinal chemistry program targeting protein-protein interactions.</p> <p>His team develops inhibitors of proteins that drive the rarest and most&nbsp;lethal human cancers, including glioblastoma, acute myeloid leukemia, multiple myeloma, and refractory medulloblastoma.&nbsp;</p> <p>鈥淲e have spent four years building a drug discovery platform that has afforded highly selective HDAC6 inhibitors,鈥 Gunning says. 鈥淭heir improved safety profile and well-retained efficacy allows for broader dosing regimens to be achieved while mitigating severe side effects from off-target inhibition.鈥</p> <p>Studies have shown the HDAC6 inhibitors have a superior synergy and safety window than current HDAC inhibitors, Gunning says.</p> <p>鈥淕iven these promising findings, we aim to improve selectivity margin, anticancer effects and oral exposure.鈥</p> </div> <div class="field field--name-field-source field--type-string field--label-hidden field__item">UTC</div> <div class="field field--name-field-top-story-hub-page- field--type-boolean field--label-above"> <div class="field__label">Top Story (Hub page)</div> <div class="field__item">Off</div> </div> Mon, 29 Mar 2021 10:56:42 +0000 lanthierj 168876 at